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Rpb1 CTD 抗体 (pSer2, Ser2)

This anti-Rpb1 CTD antibody is a 大鼠 单克隆 antibody detecting Rpb1 CTD in WB, IF, ICC, ChIP, ChIP-seq 和 IP. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 6+ publications.
产品编号 ABIN2668539
发货至: 中国

Quick Overview for Rpb1 CTD 抗体 (pSer2, Ser2) (ABIN2668539)

抗原

Rpb1 CTD (RNA Polymerase II CTD)

适用

  • 23
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 10
  • 9
  • 4
大鼠

克隆类型

  • 14
  • 9
单克隆

标记

  • 23
This Rpb1 CTD antibody is un-conjugated

应用范围

  • 23
  • 17
  • 14
  • 9
  • 6
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq), Immunoprecipitation (IP)

克隆位点

3E10
  • 抗原表位

    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    pSer2, Ser2

    纯化方法

    Protein G Chromatography

    免疫原

    This RNA pol II CTD pSer2 antibody was raised against a peptide containing the RNA pol II CTD sequence phosphorylated at serine 2.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1 μg/μL

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

    储存条件

    -80 °C

    储存方法

    Antibodies in solution can be stored at -80 °C for 2 years.

    有效期

    6 months
  • Chung, Xu, Fuchs, Mund, Lange, Staege, Schubert, Bian, Dunkel, Eberharter, Regnard, Klinker, Meierhofer, Cozzuto, Winterpacht, Di Croce, Min, Will, Kinkley: "PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3." in: eLife, Vol. 5, (2016) (PubMed).

    Harlen, Trotta, Smith, Mosaheb, Fuchs, Churchman: "Comprehensive RNA Polymerase II Interactomes Reveal Distinct and Varied Roles for Each Phospho-CTD Residue." in: Cell reports, Vol. 15, Issue 10, pp. 2147-2158, (2016) (PubMed).

    Catania, Pidoux, Allshire: "Sequence features and transcriptional stalling within centromere DNA promote establishment of CENP-A chromatin." in: PLoS genetics, Vol. 11, Issue 3, pp. e1004986, (2015) (PubMed).

    Eifler, Shao, Bartholomeeusen, Fujinaga, Jäger, Johnson, Luo, Krogan, Peterlin: "Cyclin-dependent kinase 12 increases 3' end processing of growth factor-induced c-FOS transcripts." in: Molecular and cellular biology, Vol. 35, Issue 2, pp. 468-78, (2014) (PubMed).

    Hintermair, Heidemann, Koch, Descostes, Gut, Gut, Fenouil, Ferrier, Flatley, Kremmer, Chapman, Andrau, Eick: "Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation." in: The EMBO journal, Vol. 31, Issue 12, pp. 2784-97, (2012) (PubMed).

    Chapman, Heidemann, Albert, Mailhammer, Flatley, Meisterernst, Kremmer, Eick: "Transcribing RNA polymerase II is phosphorylated at CTD residue serine-7." in: Science (New York, N.Y.), Vol. 318, Issue 5857, pp. 1780-2, (2007) (PubMed).

  • 抗原

    Rpb1 CTD (RNA Polymerase II CTD)

    别名

    RNA Pol II CTD

    分子量

    240 kDa

    基因ID

    5430
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